bassyn.blogg.se - Digoxin antidote

The complexes accumulate in the blood and are expelled by the kidney. It works by binding to the digoxin, rendering it unable to bind to its action sites on target cells. Because it is relatively new, no drug interaction studies have been performed yet.

The patient must be closely monitored for anaphylactic shock, and anyone allergic to sheep protein, papain, bromelain, or papaya extracts (papain is used to cleave the antibody into Fab and Fc fragments) should not use ovine digoxin immune fab.

swelling of the lips, tongue, face, or throatĪvoid use in hypokalemia as this drug, while reversing the effects of digitalis, will further reduce serum potassium levels and could precipitate dangerous and even fatal cardiac arrhythmias.

Side effects of digoxin immune fab may occur: digoxin level > 10 ng/ml if acute ingestion.digoxin level > 4 ng/ml if chronic ingestion.It can occur even when the serum digoxin concentration is within the therapeutic range when one of the following is present: Digoxin toxicity can emerge during long-term therapy as well as after an overdose. 4 Regulatory information and clinical studies.